Psoriatic arthritis affects several joints at the same time. Typical symptoms are painful joints, especially at rest. Further symptoms include swelling, redness and hyperthermia, as well as stiff joints. The symptoms tend to be most severe in the mornings. Those affected also tend to suffer from changes to the skin and nails with scaly patches, so-called plaques, that occur on the arms, legs and back in particular, but can also occur on the scalp.

As the systemic disease often affects other organs such as the eyes, bowel and tendons, in addition to the skin, regular preventive check-ups are important after diagnosis, in order to avoid subsequent and concomitant diseases, or treat them early. The most frequent concomitant diseases suffered by psoriatic arthritis patients include hypertension, diabetes, dyslipidemia, anxiety and depression.