Selecting the right therapy depends on a range of factors. Crohn's disease mostly tends to progress in episodes. The acute manifestation of the symptoms therefore plays an important role when deciding on therapy. Disease activity is also considered, i.e. the longer-term frequency, duration and severity of the episodes, as is occurrence of concomitant diseases.
In general, the following therapeutic approaches are possible:
Taking antibiotics can help abscesses and fistulas to heal. Taking so-called aminosalicylates, which are anti-inflammatory, is recommended for light symptoms.
Using corticosteroids and immunomodulators (medication that intervenes in the immune system) if the aminosalicyclates are not sufficiently effective.
Surgical procedure to remove constrictions in the bowel, drain abscesses and close fistulas